New technologies that are functioning and working in “nanometer” level, i.e. billionth of one meter are called “Nanotechnologies”. Starting with 1990s, “Nanotechnologies” are being intensely investigated and eventually becoming one of the most important scientific and technological fields of 21st Century. In this universe of this unbelievably small 10-9 meter dimension or millionth of one mm level, science and technology have specifically different and unusual “properties”. In future worlds, “nano-machineries”, “nano-robots”, “nano-systems” that are functioning and performing in such small spaces i.e., billionth of one meter , will eventually shape, construct the future World. For future mechanical engineers, basic principles of nanotechnologies, process and applications knowledge and completing engineering education with such information have utmost importance. Along with this course, definitions, classifications, general view of “nanotechnologies” will be discussed and other important subjects closely linked to mechanical engineering will be overviewed. The course will start with fundamental definitions, descriptions, classification and examples related to “nano” and then basic processing methods (including nano-composites and carbon nanotubes) and nano-systems, nano-manufacturing and nano-electromechanics (NEMS) closely related to mechanical engineering will be shown and discussed. The course will specifically concentrated on applications in the fields of automotives, machinery-manufacturing, defense, space-aviation, textiles, energy. Students in mechanical engineering education will eventually receive extensive information, learning and guidance for future specialization with all these topics given above.