History of nanoscience and nanotechnology, highlights of major accomplishments, chemistry of nanotechnology (fuel cells, encapsulation, nanoparticles, carbon nanotubes, nanocomposites, self-assembly, surface chemistry), current research tools and techniques (microscopy, simulation, crystallography, interferometry, chemical synthesis, plasma treatments, lithography), manufacturing processes (self-assembly, lithography, etc.), recent progress in microscopy, software, materials, electronics, energy and life sciences, approach to nanotechnology around the world (governments, universities, commercial enterprises) current commercial activity (nanoscale devices, life sciences, etc.), future. Laboratory experiments for underlying concepts accompany lectures.